TRICHOSTATIN A STABILIZES THE EXPRESSION OF PLURIPOTENT GENES IN HUMAN MESENCHYMAL STEM CELLS DURING EX VIVO EXPANSION.

Trichostatin A stabilizes the expression of pluripotent genes in human mesenchymal stem cells during ex vivo expansion.

BACKGROUND: Mesenchymal stem cells (MSCs) have been considered as ideal cells for the treatment of a variety of diseases.However, aging and spontaneous differentiation of MSCs during culture expansion dampen their effectiveness.Previous studies suggest that ex vivo aging of MSCs is largely caused by epigenetic changes particularly a decline of hist

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The Impact of COVID-19 on Medical Education: An Indian Perspective

The Coronavirus Disease-19 (COVID-19) caused by Severe Acute Respiratory Syndrome Garden Ornament Coronavirus 2 (SARS-CoV-2) has affected the human race across continents.Besides factories, food supply, transportation and travel industry; the education sector including medical education has also been adversely affected.It has been learned from expe

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Xantophyll-Zyklus in Chlamydomonas reinhardii

During the xanthophyll cycle, which occurs upon illumination in thylakoid membranes of chloroplasts, violaxanthin is transformed via antheraxanthin into zeaxanthin.Not all of the violaxanthin, which seems to be present in a loosely and a more tightly bound form in pigment-protein complexes, participates in the cycle.Here we study the xanthophyll cy

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